Study Examines Celebrex and Heart Attacks
The Associated Press
March 1, 2006

People taking the pain reliever Celebrex were at nearly twice the risk for heart attacks as those using rival treatments, according to a study released Wednesday conducted by New Zealand's Medical Research Institute.

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FDA Announces Strong Warnings for Painkillers
The New York Times
April 8, 2005

Federal drug regulators issued sweeping warnings Thursday that many popular painkillers could hurt the heart, stomach or skin, and they persuaded Pfizer to withdraw its pain pull Bextra, once a strong seller.

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Celebrex Gets Warning
WebMD
April 7, 2005

The popular arthritis drug Bextra will be pulled from the U.S. market under a decision issued by the FDA Thursday.

Celebrex, a closely related drug also made by Pfizer, from the class of pain relievers known as Cox-2 inhibitors, will be allowed to remain on the market. But it will be forced to carry strict new warnings alerting doctors and patients that it elevates the risk of heart attacks and strokes, the FDA says.

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Celebrex Research Indicates Heart Risk
San Francisco Chronicle
December 18, 2004

A clinical trial of the blockbuster arthritis drug Celebrex was shut down Friday after researchers found an increase in the risk of serious heart disease and strokes in those taking the drug, the same side effects that caused the related painkiller Vioxx to be taken off the market this fall.

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Maker Cites Heart Risk in Celebrex
The Boston Globe
December 18, 2004

The National Cancer Institute halted a three-year international study using Celebrex because long-term use of the painkiller at high doses more than triped risk of heart problems, the drug's manufacturer said yesterday.

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FDA: Consider 'Alternative' To Celebrex
CNN Health
December 18, 2004

With a new study that indicates the nation's leading arthritis painkiller could raise the risk of heart attacks, the Food and Drug Administration advised doctors Friday to consider "alternative therapy" to Celebrex.

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Consider Avoiding Celebrex, FDA Advises Doctors
The Arizona Republic
December 18, 2004

The Food and Drug Administration said Friday that the government is advising physicians to consider prescribing drugs other than Celebrex to their patients.

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